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Article
Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva
African Journal of Pharmacy and Pharmacology (2012)
  • Noorzurani Robson, Associate Prof. Dr.
  • A. J. Bond
  • K. Wolff
Abstract

Salivary nicotine and salivary cotinine is widely used in clinical and epidemiological studies to validate smoking cessation. However, the reported collection for salivary nicotine and salivary cotinine vary by technique and duration. This study investigated the influence of salivary collection by unstimulation and stimulation technique of the concentration of salivary nicotine and salivary cotinine. It was found that unstimulated technique produced the highest salivary nicotine concentration, whereas stimulated technique produced the highest salivary cotinine concentration. The results of this study suggest that it is important to standardise salivary nicotine and cotinine collection technique.

Publication Date
Winter February, 2012
Citation Information
Noorzurani Robson Associate Prof. Dr., A. J. Bond, and K. Wolff. "Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva" African Journal of Pharmacy and Pharmacology 4.2 (2012): 61-65.