Students in middle school often learn basic genetics and gain experience using a Punnett Square analysis to determine probable genotype and phenotype outcomes for a family. What students may not learn is how these probabilities relate to the overall population. Probability is an integral part of genetics and heredity. Understanding what is meant by “probability” and how it applies to genetics is an important focus in the CCSS. One way to teach these concepts is to tap into popular literature. In this session, we will explore the genetics and probability behind the character, Auggie, in the book, Wonder, by R.J. Palacio.