Article
Split, Splitless, and Beyond—Getting the Most from Your Inlet
LCGC North America
(2018)
Abstract
While capillary gas chromatography has been undergoing a renaissance, with new columns, detectors, data systems, and multidimensional separations, the classical inlets have remained the same: We are still injecting liquid samples with syringes into split and splitless inlets, as we have for nearly 50 years. Split and splitless injections present several well-known, and some not-so-well known, challenges, mostly arising from heating of the inlet, that make sample injection and inlets a major hurdle for gas chromatographers. These challenges and some ideas for mitigating them are discussed and a case is made for renewed exploration of the cool inlets and injection techniques: cool on-column and programmed temperature vaporization.
Disciplines
Publication Date
July 1, 2018
Citation Information
Nicholas Snow. "Split, Splitless, and Beyond—Getting the Most from Your Inlet" LCGC North America Vol. 36 Iss. 7 (2018) p. 448 - 454 ISSN: 1939-1889 Available at: http://works.bepress.com/nicholas_snow/64/