Article
65% Parahydrogen from a Liquid Nitrogen Cooled Generator
Journal of Magnetic Resonance
(2022)
Abstract
The isomeric enrichment of parahydrogen (pH2) gas is readily accomplished by lowering the gas temperature in the presence of a catalyst. This enrichment is often pursued at two distinct temperatures: ∼51% pH2 is generated at liquid nitrogen temperatures (77 K), while nearly 100% pH2 can be produced at 20 K. While the liquid nitrogen cooled generator is attractive due to the low cost of entry, there are benefits to having access to greater than 51% pH2 for enhanced NMR applications. In this work, we introduce a low-cost modification to an existing laboratory-constructed liquid nitrogen cooled pH2 generator that provides ∼ 65% pH2. This modification takes advantage of vacuum-mediated boiling point suppression of liquid nitrogen, allowing the temperature of the liquid to be lowered from 77 K to nitrogen’s triple point of 63 K. The reduced temperature allowed for the generation of parahydrogen fractions of 63–67% at gas flow rates from 20 to 1000 standard cubic centimeters per minute. We compare this to equivalent experiments that did not utilize the temperature-lowering effects of pressure reduction; these controls generally maintained pH2 fractions of ∼ 50%. All results (experimental and control) agree with the theoretically expected parahydrogen generation at these temperatures. This straightforward modification to an existing pH2 generator may be of interest to a broad range of scientists involved with parahydrogen research by introducing a simple and low-cost entryway to increased pH2 fractions using a conventional liquid nitrogen cooled generator.
Keywords
- Parahydrogen,
- Hyperpolarization,
- Liquid nitrogen,
- Boiling point suppression
Disciplines
Publication Date
June 16, 2022
DOI
https://doi.org/10.1016/j.jmr.2022.107249
Citation Information
Yash Mhaske, Elodie Sutter, James Daley, Christopher Mahoney, et al.. "65% Parahydrogen from a Liquid Nitrogen Cooled Generator" Journal of Magnetic Resonance Vol. 341 (2022) p. 107249 Available at: http://works.bepress.com/nicholas-whiting/27/