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Article
Fabrication and characterization of chitosan coated and uncoated pcl/ha/ppy composite scaffoldsusing freeze drying technique
Texas Undergraduate Medical Academy Faculty Publications
  • Sharon Kalu Joseph Ufere, Universiti Teknologi Malaysia
  • Naznin Sultana, Universiti Teknologi Malaysia
Document Type
Article
Publication Date
1-1-2016
Abstract

Chitosan is an abundantly common, naturally occurring, polysaccharide biopolymer. In this study, chitosan was used to coat previously fabricated conductive Polycaprolactone/Hydroxyapatite/Polypyrrole (PCL/HA/PPY) composite scaffold and the properties of the coated and non-coated scaffolds were investigated and compared. The morphology of the chitosan coated and non-coated scaffolds were characterized using a scanning electron microscope (SEM). The wettability was determined using a water contact angle measuring system. Furthermore, water uptake was determined by measuring the water absorption of each sample before and after coated with chitosan. Water contact angle result revealed an increase in wettability of the scaffolds ranging from 108° ± 4.2 down to 59.4° ± 0.7. On the other hand, the coated sample showed a higher water uptake than the non-coated sample. The results indicated that coating with chitosan was important to increase water absorption of composite scaffold, rendering it more hydrophilic.

Citation Information
Sharon Kalu Joseph Ufere and Naznin Sultana. "Fabrication and characterization of chitosan coated and uncoated pcl/ha/ppy composite scaffoldsusing freeze drying technique" (2016)
Available at: http://works.bepress.com/naznin-sultana/49/