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Article
C-reactive protein concentration in dogs with chronic valvular disease
Journal of Veterinary Internal Medicine (2006)
  • J E Rush
  • Nathan D Lee, Tufts University
  • L M Freeman
  • B Brewer
Abstract
The purpose of the study reported here was to determine whether dogs with chronic valvular disease have increased plasma C-reactive protein concentration, compared with that in clinically normal dogs. Blood was collected from 47 dogs with physical and echocardiographic evidence of chronic valvular disease and from 20 healthy controls. C-reactive protein concentration was determined with a commercial canine C-reactive protein enzyme immunoassay. Compared with controls, dogs with chronic valvular disease had higher plasma concentration of C-reactive protein (median 2.17 g/mL [range, 0.86-33.8 g/mL]) versus (1.43 g/mL [range, 0.84-4.99 g/mL]; P<.001). C-reactive protein concentration was not related to the presence of congestive heart failure or murmur grade. The results of this study suggest that increased concentration of C- reactive protein is found in dogs with chronic valvular disease.
Disciplines
Publication Date
2006
Citation Information
J E Rush, Nathan D Lee, L M Freeman and B Brewer. "C-reactive protein concentration in dogs with chronic valvular disease" Journal of Veterinary Internal Medicine Vol. 20 Iss. 3 (2006)
Available at: http://works.bepress.com/nathan_lee/2/