Article
CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Document Type
Article
Publication Date
1-2-2019
URL with Digital Object Identifier
https://doi.org/10.1523/JNEUROSCI.3496-17.2018
Disciplines
Abstract
The CCCTC-binding factor (CTCF) is a central regulator of chromatin topology recently linked to neurodevelopmental disorders such as intellectual disability, autism, and schizophrenia. The aim of this study was to identify novel roles of CTCF in the developing mouse brain. We provide evidence that CTCF is required for the expression of the LIM homeodomain factor LHX6 involved in fate determination of cortical interneurons (CINs) that originate in the medial ganglionic eminence (MGE). Conditional
Citation Information
Adrienne Elbert, Daniel Vogt, Ashley Watson, Michael Levy, et al.. "CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons." The Journal of neuroscience : the official journal of the Society for Neuroscience Vol. 39 Iss. 1 (2019) p. 177 - 192 Available at: http://works.bepress.com/nathalie-berube/2/
Also available open access in The Journal of Neuroscience V.39, NO 1 at https://doi.org/10.1523/JNEUROSCI.3496-17.2018