Thesis
Low-cost, Wireless Optical Oximeter for Monitoring of Brain Function in High-risk Pediatric Population
(2016)
Abstract
Nearly 4 million neonates die every year due to brain injuries, most caused by hypoxia. Neonatal ICU requires newborns with critical health conditions to be monitored continuously calling for the need of a non-invasive, compact and portable device. However, commercial devices are mostly bulky and/or expensive. The neonatal mortality is higher in under-developed countries, where such expensive and large devices are not affordable. Hence, my thesis focuses on building first generation compact, inexpensive, and wireless device that can monitor and provide feedback to clinicians during intervention. This approach is based on light absorption by oxy- and deoxy-hemoglobin chromophores. The total cost of this device is less than $100, which is lower than commercial devices (>$10K). The device has SNR of 65 dB. It was successfully tested by the arm occlusion protocol, which allowed measuring real-time oxygenation changes in vivo. Overall, the first generation device shows promise for future clinical studies.
Keywords
- brain,
- neonates
Disciplines
Publication Date
Fall November 2, 2016
Degree
Master of Science in Biomedical Engineering (MSBME)
Department
Biomedical, Industrial & Human Factors Engineering
Citation Information
Zahra Meghjani. "Low-cost, Wireless Optical Oximeter for Monitoring of Brain Function in High-risk Pediatric Population" (2016) Available at: http://works.bepress.com/nasser_kashou/56/