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Article
Nonlinear Neural Network for Hemodynamic Model State and Input Estimation using fMRI Data
Biomedical Signal Processing and Control
  • Ayman M. Karam
  • Taous Meriem Laleg-Kirati
  • Chadia Zayane
  • Nasser H. Kashou, Wright State University - Main Campus
Document Type
Article
Publication Date
11-1-2014
Abstract
Originally inspired by biological neural networks, artificial neural networks (ANNs) are powerful mathematical tools that can solve complex nonlinear problems such as filtering, classification, prediction and more. This paper demonstrates the first successful implementation of ANN, specifically nonlinear autoregressive with exogenous input (NARX) networks, to estimate the hemodynamic states and neural activity from simulated and measured real blood oxygenation level dependent (BOLD) signals. Blocked and event-related BOLD data are used to test the algorithm on real experiments. The proposed method is accurate and robust even in the presence of signal noise and it does not depend on sampling interval. Moreover, the structure of the NARX networks is optimized to yield the best estimate with minimal network architecture. The results of the estimated neural activity are also discussed in terms of their potential use.
DOI
10.1016/j.bspc.2014.07.004
Citation Information
Ayman M. Karam, Taous Meriem Laleg-Kirati, Chadia Zayane and Nasser H. Kashou. "Nonlinear Neural Network for Hemodynamic Model State and Input Estimation using fMRI Data" Biomedical Signal Processing and Control Vol. 14 (2014) p. 240 - 247 ISSN: 17468094
Available at: http://works.bepress.com/nasser_kashou/21/