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PRogram In Support of Moms (PRISM): a pilot group randomized controlled trial of two approaches to improving depression among perinatal women
UMass Center for Clinical and Translational Science Supported Publications
  • Nancy Byatt, University of Massachusetts Medical School
  • Tiffany A. Moore Simas, University of Massachusetts Medical School
  • Kathleen Biebel, University of Massachusetts Medical School
  • Padma Sankaran, University of Massachusetts Medical School
  • Lori Pbert, University of Massachusetts Medical School
  • Linda Weinreb, University of Massachusetts Medical School
  • Douglas M. Ziedonis, University of California, San Diego
  • Jeroan J. Allison, University of Massachusetts Medical School
UMMS Affiliation
Department of Psychiatry; Systems and Psychosocial Advances Research Center; Department of Obstetrics and Gynecology; Department of Medicine, Division of Preventive and Behavioral Medicine; Department of Family Medicine and Community Health; Department of Quantitative Health Sciences
Publication Date
10-10-2017
Document Type
Article
Abstract
PURPOSE: This pilot study was designed to inform a larger effectiveness trial by: (1) assessing the feasibility of the PRogram In Support of Moms (PRISM) and our study procedures; and, (2) determining the extent to which PRISM as compared to an active comparison group, the Massachusetts Child Access Psychiatry Program (MCPAP) for Moms alone, improves depression among perinatal women. METHODS: Four practices were randomized to either PRISM or MCPAP for Moms alone, a state-wide telephonic perinatal psychiatry program. PRISM includes MCPAP for Moms plus implementation assistance with local champions, training, and implementation of office prompts and procedures to enhance depression screening, assessment and treatment. Patients with Edinburgh Postnatal Depression Scales (EPDS) > /= 10 were recruited during pregnancy, and completed the EPDS and a structured interview at baseline and 3-12 weeks' postpartum. RESULTS: Among MCPAP for Moms alone practices, patients' (n = 9) EPDS scores improved from 15.22 to 10.11 (p = 0.010), whereas in PRISM practices patients' (n = 21) EPDS scores improved from 13.57 to 6.19 (p = 0.001); the between groups difference-of-differences was 2.27 (p = 0.341). CONCLUSIONS: PRISM was beneficial for patients, clinicians, and support staff. Both PRISM and MCPAP for Moms alone improve depression symptom severity and the percentage of women with an EPDS > 10. The improvement difference between groups was not statistically significant due to limited power associated with small sample size.
Keywords
  • UMCCTS funding,
  • maternal depression,
  • obstetrics,
  • perinatal metal health,
  • post-natal depression,
  • mental health
DOI of Published Version
10.1080/0167482X.2017.1383380
Source
J Psychosom Obstet Gynaecol. 2017 Oct 10:1-10. doi: 10.1080/0167482X.2017.1383380. [Epub ahead of print] Link to article on publisher's site
Related Resources
Link to Article in PubMed
PubMed ID
28994626
Citation Information
Nancy Byatt, Tiffany A. Moore Simas, Kathleen Biebel, Padma Sankaran, et al.. "PRogram In Support of Moms (PRISM): a pilot group randomized controlled trial of two approaches to improving depression among perinatal women" (2017) ISSN: 0167-482X (Linking)
Available at: http://works.bepress.com/nancy_byatt/49/