Specific Inhibition of RH0(D) Antibody by Sialic AcidsScience
AbstractAgglutination of RhO(D) erythrocytes by specific antiserum was inhibited by crude and crystalline N-acetylneuraminic acid, less inhibited by its glycoyl derivative, and weakly inhibited by its degradation product, N-acetyl-mannosamine, and by D-mannose. A brain ganglioside containing neuraminic acid and a Pseudomonas polysaccharide were even more inhibitory. Inhibition was specific for anti-D sera.
Citation InformationMatthew C. Dodd, Nancy J. Bigley and Virginia B. Geyer. "Specific Inhibition of RH0(D) Antibody by Sialic Acids" Science Vol. 132 Iss. 3437 (1960) p. 1398 - 1399 ISSN: 0036-8075
Available at: http://works.bepress.com/nancy_bigley/25/