Autoimmune Response in Rabbits Injected with Rat and Rabbit Liver RibosomesScience
AbstractAutoimmune hemolytic anemia and leukopenia, circulating autoantibodies for erythrocytes, leukocytes, and ribosomes; pathological changes in liver, spleen, heart, brain, and kidneys were produced in rabbits injected with rat or rabbit liver ribosomes. The hematologic and pathologic changes were reproduced by injection of anti-ribosomal serum into normal rabbits. The autoantibody specificity was related primarily to nucleotides and nucleosides.
Citation InformationMatthew C. Dodd, Nancy J. Bigley, Virginia B. Geyer, Francis W. McCoy, et al.. "Autoimmune Response in Rabbits Injected with Rat and Rabbit Liver Ribosomes" Science Vol. 137 Iss. 3531 (1962) p. 688 - 689 ISSN: 0036-8075
Available at: http://works.bepress.com/nancy_bigley/21/