An Industrial Tomography Scanner (ITS) Was Designed and Developed to Study and Quantify the Phase Distribution in a Two-Phase Flow Pilot Scale Monolith Reactor that Was 24 In. (0.60 M) in Diameter and 192 In. (4.9 M) in Height. the Monolith Reactor Was Operated Co-Current Up-Flow in the Taylor Flow Regime with Water as the Liquid Phase and Air as the Gas Phase. the Cross-Sectional Holdup Distributions Were Measured at Three Axial Elevations. the Operating Conditions Were Selected to Bracket Commercial Operating Conditions for Fixed Bed Monolithic Reactor Systems. the Results Show that its Can Capture the Flow Features in a Large Diameter Column. Also, the Findings Suggest the Need for Careful Design of the Internals of the Reactor. Spatial Resolution Down to 1.5 Cm Was Obtained So that Gross Phase Maldistribution Could Be Reliably Observed. However, Improvement is Needed for the its to Be Effectively Utilized in Industry. © 2006 Elsevier B.V. All Rights Reserved.