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Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
Materials letters (2012)
  • Iqbal N
  • Abdul Kadir MR
  • Nik Malek NAZ
  • Mahmooda NH
  • Murali MR, University of Malaya
  • Kamarul T, University of Malaya
Abstract

Synthesis of nanosized particles of silver-doped hydroxyapatite (Ag-HA) as an antibacterial agent is of potential importance in managing infections associated with surgical implants. However, the process of synthesizing this agent is time consuming and inefficient. To overcome this problem, a rapid method for synthesizing nano-sized Ag-doped hydroxyapatite (Ag-HA) [Ca10−xAgx(PO4)6(OH)2] (x=0.03–0.5) using microwave irradiation for 10 min at 800 W is proposed. The materials were characterized using XRD, FTIR, FESEM and EDX. Antibacterial behavior of the Ag-HA samples were evaluated using disc diffusion technique and results demonstrated good activity against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli.

Keywords
  • Biomaterial,
  • Hydroxyapatite,
  • Nano particles,
  • Microwave irradiation,
  • Antibacterial activity
Publication Date
2012
Citation Information
Iqbal N, Abdul Kadir MR, Nik Malek NAZ, Mahmooda NH, et al.. "Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties" Materials letters Vol. 89 (2012)
Available at: http://works.bepress.com/muralimalligaraman/16/