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Cytokinins: Wide-Spread Signaling Hormones from Plants to Humans with High Medical Potential
  • Moustafa Fathy, Minia University
  • Sahar M. Saad Eldin, Minia University
  • Muhammad Naseem, Zayed University
  • Thomas Dandekar, Biozentrum der Universität Würzburg
  • Eman M. Othman, Minia University
Document Type
Publication Date

Nature is a rich source of biologically active novel compounds. Sixty years ago, the plant hormones cytokinins were first discovered. These play a major role in cell division and cell differentiation. They affect organogenesis in plant tissue cultures and contribute to many other physiological and developmental processes in plants. Consequently, the effect of cytokinins on mammalian cells has caught the attention of researchers. Many reports on the contribution and potential of cytokinins in the therapy of different human diseases and pathophysiological conditions have been published and are reviewed here. We compare cytokinin effects and pathways in plants and mammalian systems and highlight the most important biological activities. We present the strong profile of the biological actions of cytokinins and their possible therapeutic applications.

  • biological activities,
  • cytokinins,
  • mammalian system,
  • phytohormones,
  • plant system
Creative Commons License
Creative Commons Attribution 4.0 International
Indexed in Scopus
Open Access
Open Access Type
Gold: This publication is openly available in an open access journal/series
Citation Information
Moustafa Fathy, Sahar M. Saad Eldin, Muhammad Naseem, Thomas Dandekar, et al.. "Cytokinins: Wide-Spread Signaling Hormones from Plants to Humans with High Medical Potential" Nutrients Vol. 14 Iss. 7 (2022) ISSN: <a href="" target="_blank">2072-6643</a>
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