|Present||Associate Professor, Department of Chemistry and Chemical Biology, Northeastern University|
Medicinal chemistry and Chemical technology
417 Egan Research Center
360 Huntington Ave.
Boston, MA 02115
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs ...
Chemistry and Chemical Biology Faculty Publications (2012)
In this report we describe our ongoing target repurposing efforts focused on discovery of inhibitors of the essential trypanosomal phosphodiesterase ...
The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors ...
Chemistry and Chemical Biology Faculty Publications (2011)
Background Target repurposing utilizes knowledge of "druggable" targets obtained in one organism and exploits this information to pursue new potential ...
Identification and characterization of Kava-derived compounds mediating TNF-α suppression
Chemistry and Chemical Biology Faculty Publications (2009)
There is a substantial unmet need for new classes of drugs that block TNF-α-mediated inflammation, and particularly for small molecule ...