The purpose of this paper is to propose a Lean Six Sigma (LSS) course curriculum for healthcare administration and management majors. It identifies the relevant opportunities and challenges for applying LSS within the healthcare industry. The paper also discusses the cultural changes necessary to provide an appropriate

climate for its long-term success. This work contains a comprehensive description of the body of knowledge in LSS, which were successful in applied engineering. Additionally, the paper describes how LSS may be applied in the hospital setting to improve processes in patient-care services. Upon successful completion of the course, the healthcare administration managers would not only acquire comprehensive understanding by learning theory and but also completion of term projects by applying it to case studies. While obstacles to LSS implementation exist, the process improvements and resulting cultural changes are worthwhile and noteworthy. The paper serves as a guide for how LSS methodology can be utilized in the healthcare-education setting. It may not touch all the aspects of LSS. Other researchers and practitioners may use the paper as a practical orientation to LSS in the university setting.