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Article
Neuroimaging of tuberculous myelitis: analysis of ten cases and review of literature
Journal of Neuroimaging
  • Mohammad Wasay, Aga Khan University
  • Hiba Arif, Aga Khan University
  • Bhojo Khealani, Aga Khan University
  • Humera Ahsan, Aga Khan University
Publication Date
7-1-2006
Document Type
Article
Abstract

We retrospectively reviewed the clinical and neuroimaging features of 10 patients with tuberculous myelitis. The most common presenting symptoms were fever (70%) and paraplegia (60%). Bladder and bowel symptoms were present in 90% patients. On MRI, the involvement of the cervical/thoracic segment of the spinal cord was most commonly seen (90%). The most consistent finding was hyperintense signals on T2-weighted MRI. T1-weighted images showed isointense (n= 5) and hypointense (n= 4) signals in the spinal cord lesions. Post-contrast enhancement was present in 6 patients, epidural enhancement in 4 patients, and cord swelling in 2 patients.

We reviewed more than 250 published cases with the diagnosis of tuberculous myelitis and radiculomyelitis with special attention to MRI findings. It is predominantly a disease of the thoracic spinal cord. Most spinal cord lesions appear as hyperintense on T2 and iso- or hypointense on T1-weighted images. MRI findings in patients with spinal cord tuberculosis have both diagnostic and prognostic significance. Cord atrophy or cavitation and the presence of syrinx on MRI may be associated with poor outcome.

Citation Information
Mohammad Wasay, Hiba Arif, Bhojo Khealani and Humera Ahsan. "Neuroimaging of tuberculous myelitis: analysis of ten cases and review of literature" Journal of Neuroimaging Vol. 16 Iss. 3 (2006) p. 197 - 205
Available at: http://works.bepress.com/mohammad_wasay/76/