Article
A conserved juxtacrine signal regulates synaptic partner recognition in C. elegans
Neural Development
(2011)
Abstract
Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets.
Disciplines
Publication Date
2011
Publisher Statement
This article is licensed under a Creative Commons Attribution 2.0 License. The publisher's version of the article may be found online at: http://dx.doi.org/10.1038/nn.3065.
Citation Information
J R Park, P L Knezevich, W Wung, S N O'Hanlon, et al.. "A conserved juxtacrine signal regulates synaptic partner recognition in C. elegans" Neural Development Vol. 6 Iss. 28 (2011) Available at: http://works.bepress.com/miri_vanhoven/2/