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Article
Effects of dexamethasone on phospholipase activities in palate mesenchyme cells in vitro.
Teratology
  • K P Chepenik
  • Mindy George-Weinstein, Philadelphia College of Osteopathic Medicine
  • R M Greene
Document Type
Article
Publication Date
8-1-1985
Abstract

Treatment of primary cultures of palate mesenchyme cells from AJAX strain embryos with dexamethasone inhibited only phospholipase activity expressed at pH 7.5. A similar treatment did not have such an effect on palate mesenchyme cells from C57BL/6J strain embryos. Since the AJAX strain embryo is sensitive to the induction of cleft palate by exogenous glucocorticoids and the C57BL/6J strain is less so, these data allow consideration of phospholipase activity as a site of regulation for development of the palate.

PubMed ID
4035584
Comments

This article was published in Teratology, Volume 32, Issue 1, Pages 119-123.

The published version is available at http://dx.doi.org/10.1002/tera.1420320116.

Copyright © 1985.

Citation Information
K P Chepenik, Mindy George-Weinstein and R M Greene. "Effects of dexamethasone on phospholipase activities in palate mesenchyme cells in vitro." Teratology Vol. 32 Iss. 1 (1985) p. 119 - 123
Available at: http://works.bepress.com/mindy-george-weinstein/23/