Article
Update on congenital cytomegalovirus infection: Prenatal prevention, newborn diagnosis, and management
The Canadian Paediatric Society
(2020)
Abstract
Cytomegalovirus (CMV) is the leading cause of congenital infection and the most common cause of non-genetic sensorineural hearing loss (SNHL) in childhood. Although most infected infants are asymptomatic at birth, the risk for SNHL and other neurodevelopmental morbidity makes congenital CMV (cCMV) a disease of significance. Adherence to hygienic measures in pregnancy can reduce risk for maternal CMV infection. The prompt identification of infected infants allows early initiation of surveillance and management. A multidisciplinary approach to management is critical to optimize outcomes in affected infants.
Keywords: Congenital infection; Cytomegalovirus (CMV); Neurodevelopmental sequelae; Polymerase chain reaction (PCR); Sensorineural hearing loss (SNHL); Valganciclovir
Disciplines
Publication Date
September, 2020
Citation Information
Michelle Barton-Forbes, A. Michael Forrester and Jane McDonald. "Update on congenital cytomegalovirus infection: Prenatal prevention, newborn diagnosis, and management" The Canadian Paediatric Society (2020) Available at: http://works.bepress.com/michelle-barton-forbes/5/