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Selected Works of Michelle Arnold
Article
A Randomized Feasibility Pilot Trial of Hearing Treatment for Reducing Cognitive Decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study
Alzheimer's & Dementia: Translational Research & Clinical Interventions
  • Jennifer A. Deal, Johns Hopkins Bloomberg School of Public Health, Baltimore
  • Marilyn S. Albert, Johns Hopkins School of Medicine, Baltimore, MD
  • Michelle Arnold, University of South Florida
  • Shrikant I. Bangdiwala, University of North Carolina
  • Theresa Chisolm, University of South Florida
  • Sonia Davis, University of North Carolina
  • Ann Eddins, University of South Florida
  • Nancy W. Glynn, University of Pittsburgh School of Public Health
  • Adele M. Goman, Johns Hopkins School of Medicine, Baltimore
  • Melissa Minotti, Johns Hopkins Bloomberg School of Public Health, Hagerstown
  • Thomas Mosley, University of Mississippi Medical Center
  • George W. Rebok, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
  • Nicholas Reed, Johns Hopkins School of Medicine, Baltimore, MD
  • Elizabeth Rodgers, University of Pittsburgh School of Public Health
  • Victoria Sanchez, University of South Florida
  • A. Richey Sharrett, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
  • Josef Coresh, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
  • Frank R. Lin, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Link Find in your library
Document Type
Article
Publication Date
1-1-2017
Keywords
  • Clinical trials,
  • Cognition,
  • Dementia,
  • Epidemiology,
  • Hearing,
  • Longitudinal study,
  • Memory,
  • Presbycusis
Digital Object Identifier (DOI)
https://doi.org/10.1016/j.trci.2017.06.003
Abstract

Introduction: Hearing loss (HL) is prevalent and independently related to cognitive decline and dementia. There has never been a randomized trial to test if HL treatment could reduce cognitive decline in older adults.

Methods: A 40-person (aged 70–84 years) pilot study in Washington County, MD, was conducted. Participants were randomized 1:1 to a best practices hearing or successful aging intervention and followed for 6 months. clinicaltrials.gov Identifier: NCT02412254.

Results: The Aging and Cognitive Health Evaluation in Elders Pilot (ACHIEVE-P) Study demonstrated feasibility in recruitment, retention, and implementation of interventions with no treatment-related adverse events. A clear efficacy signal of the hearing intervention was observed in perceived hearing handicap (mean of 0.11 to −1.29 standard deviation [SD] units; lower scores better) and memory (mean of −0.10 SD to 0.38 SD).

Discussion: ACHIEVE-P sets the stage for the full-scale ACHIEVE trial (N = 850, recruitment beginning November 2017), the first randomized trial to determine efficacy of a best practices hearing (vs. successful aging) intervention on reducing cognitive decline in older adults with HL.

Citation / Publisher Attribution

Alzheimer's & Dementia: Translational Research & Clinical Interventions, v. 3, issue 3, p. 410-415

Citation Information
Jennifer A. Deal, Marilyn S. Albert, Michelle Arnold, Shrikant I. Bangdiwala, et al.. "A Randomized Feasibility Pilot Trial of Hearing Treatment for Reducing Cognitive Decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study" Alzheimer's & Dementia: Translational Research & Clinical Interventions Vol. 3 Iss. 3 (2017) p. 410 - 415
Available at: http://works.bepress.com/michelle-arnold/12/