Skip to main content
profile image
Selected Works of Michelle Arnold
Article
Hearing Treatment for Reducing Cognitive Decline: Design and Methods of the Aging and Cognitive Health Evaluation in Elders Randomized Controlled Trial
Alzheimer's & Dementia: Translational Research & Clinical Interventions
  • Jennifer A. Deal, Johns Hopkins Bloomberg School of Public Health, Baltimore
  • Adele M. Goman, Johns Hopkins School of Medicine, Baltimore
  • Marilyn S. Albert, Johns Hopkins School of Medicine, Baltimore
  • Michelle L. Arnold, University of South Florida
  • Sheila Burgard, University of North Carolina
  • Theresa Chisolm, University of South Florida
  • David Couper, University of North Carolina
  • Nancy W. Glynn, University of Pittsburgh Graduate School of Public Health
  • Theresa Gmelin, University of Pittsburgh
  • Kathleen M. Hayden, Wake Forest School of Medicine, Winston-Salem, NC
  • Thomas Mosley, University of Mississippi Medical Center
  • James S. Pankow, University of Minnesota School of Public Health
  • Nicholas Reed, Johns Hopkins School of Medicine, Baltimore
  • Victoria Sanchez, University of South Florida
  • A. Richey Sharrett, Johns Hopkins Bloomberg School of Public Health, Baltimore
  • Sonia D. Thomas, RTI International, Research Triangle Park, NC
  • Josef Coresh, Johns Hopkins Bloomberg School of Public Health, Baltimore
  • Frank R. Lin, Johns Hopkins Bloomberg School of Public Health, Baltimore
Download Find in your library
Document Type
Article
Publication Date
1-1-2018
Keywords
  • Clinical trials,
  • Cognition,
  • Dementia,
  • Epidemiology,
  • Hearing,
  • Longitudinal study,
  • Memory,
  • Presbycusis
Digital Object Identifier (DOI)
https://doi.org/10.1016/j.trci.2018.08.007
Abstract

Introduction: Hearing impairment is highly prevalent and independently associated with cognitive decline. The Aging and Cognitive Health Evaluation in Elders study is a multicenter randomized controlled trial to determine efficacy of hearing treatment in reducing cognitive decline in older adults. Clinicaltrials.gov Identifier: NCT03243422.

Methods: Eight hundred fifty participants without dementia aged 70 to 84 years with mild-to-moderate hearing impairment recruited from four United States field sites and randomized 1:1 to a best-practices hearing intervention or health education control. Primary study outcome is 3-year change in global cognitive function. Secondary outcomes include domain-specific cognitive decline, incident dementia, brain structural changes on magnetic resonance imaging, health-related quality of life, physical and social function, and physical activity.

Results: Trial enrollment began January 4, 2018 and is ongoing.

Discussion: When completed in 2022, Aging and Cognitive Health Evaluation in Elders study should provide definitive evidence of the effect of hearing treatment versus education control on cognitive decline in community-dwelling older adults with mild-to-moderate hearing impairment.

Rights Information
Creative Commons Attribution-Noncommercial-No Derivative Works 4.0
Citation / Publisher Attribution

Alzheimer's & Dementia: Translational Research & Clinical Interventions, v. 4, issue 1, p. 499-507

Citation Information
Jennifer A. Deal, Adele M. Goman, Marilyn S. Albert, Michelle L. Arnold, et al.. "Hearing Treatment for Reducing Cognitive Decline: Design and Methods of the Aging and Cognitive Health Evaluation in Elders Randomized Controlled Trial" Alzheimer's & Dementia: Translational Research & Clinical Interventions Vol. 4 Iss. 1 (2018) p. 499 - 507
Available at: http://works.bepress.com/michelle-arnold/10/