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Decoding cis-regulatory DNAs in the Drosophila genome
Current Opinion in Genetics and Development (2002)
  • Michele Markstein, University of Massachusetts - Amherst
  • Michael Levine

Cis-regulatory DNAs control the timing and sites of gene expression during metazoan development. Changes in gene expression are responsible for the morphological diversification of metazoan body plans. However, traditional methods for the identification and characterization of cis-regulatory DNAs are tedious. During the past year, computational methods have been used to identify novel cis-DNAs within the entire Drosophila genome. These methods change the way that cis-DNAs will be analyzed in future studies and offer the promise of unraveling complex gene networks.

  • cis-regulatory,
  • DNA,
  • metazoa,
  • computational analysis,
  • enhancer
Publication Date
October 1, 2002
Publisher Statement
doi: 10.1016/S0959-437X(02)00345-3
Citation Information
Michele Markstein and Michael Levine. "Decoding cis-regulatory DNAs in the Drosophila genome" Current Opinion in Genetics and Development Vol. 12 Iss. 5 (2002)
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