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Selected Works of Michael J. Doherty, MD, FAAN
Article
Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization.
Epilepsy Behav Case Rep
  • Sarah R Garson, Swedish Epilepsy Center, Seattle, WA, USA.
  • Stephen J Monteith, Swedish Neuroscience Institute, Department of Neurosurgery, Seattle, WA, USA.
  • Sheila D Smith, Swedish Neuroscience Institute, Department of Neurology, Seattle, WA, USA.
  • Bart P Keogh
  • Ryder P Gwinn, Swedish Neuroscience Institute, Department of Neurosurgery, Seattle, WA, USA; Swedish Neuroscience Institute, Department of Neurology, Seattle, WA, USA.
  • Michael J Doherty, Swedish Epilepsy Center, Seattle, WA, USA; Swedish Neuroscience Institute, Department of Neurology, Seattle, WA, USA.
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Document Type
Article
Publication Date
1-1-2019
Keywords
  • Bypass,
  • Perfusion,
  • Stenosis
Disciplines
Abstract

Objectives: To examine outcome of bilateral extracranial to intracranial (EC-IC) bypass surgeries for a Down syndrome patient with hard-to-treat epilepsy and moyamoya.

Materials and methods: Superficial temporal arteries were anastamosed using an indirect bypass technique to middle cerebral arteries bilaterally to help limit perfusion deficits and seizure controls.

Results: Two superficial temporal to middle cerebral artery indirect bypass surgeries were performed within 3 months. Post-revascularization improvements included seizure control, gait, perfusion, wakefulness, language and quality of life.

Conclusion: In patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures.

Clinical Institute
Neurosciences (Brain & Spine)
Specialty
Neurosciences
Specialty
Surgery
Citation Information
Sarah R Garson, Stephen J Monteith, Sheila D Smith, Bart P Keogh, et al.. "Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization." Epilepsy Behav Case Rep (2019)
Available at: http://works.bepress.com/michael-doherty/4/