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Selected Works of Michael J. Doherty, MD, FAAN
Article
Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset.
Epilepsy Behav Case Rep
  • Katie M Kinnear, Swedish Epilepsy Center, Seattle, WA, USA.
  • Nicole M Warner, Swedish Epilepsy Center, Seattle, WA, USA.
  • Alan M Haltiner, Swedish Epilepsy Center, Seattle, WA, USA.
  • Michael J Doherty, Swedish Epilepsy Center, Seattle, WA, USA.
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Document Type
Article
Publication Date
1-1-2018
Keywords
  • Circadian,
  • Glucose,
  • Hypometabolism,
  • Insulin,
  • Nonketotic,
  • Stimulation
Disciplines
Abstract

Objectives: To investigate if glucose levels influence seizure patterns.

Materials and methods: In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose.

Results: Left focal seizure (LFS, n = 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2).

Conclusion: Seizure onset laterality and spread vary with glucose and time of seizure.

Clinical Institute
Neurosciences (Brain & Spine)
Specialty
Neurosciences
Citation Information
Katie M Kinnear, Nicole M Warner, Alan M Haltiner and Michael J Doherty. "Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset." Epilepsy Behav Case Rep (2018)
Available at: http://works.bepress.com/michael-doherty/1/