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Highly Efficient Propagation of Random Impulse Trains Across Unmyelinated Axonal Branch Points: Modifications by Periaxonal K+ Accumulation and Sodium Channel Kinetics
Modeling in the Neurosciences: From Biological Systems to Neuromimetic Robotics
  • Melvyn D. Goldfinger, Wright State University - Main Campus
Document Type
Book Chapter
Publication Date
1-1-2005
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Abstract

This chapter addresses the divergence of axonal information at branch points, specifically comparing the extent to which impulse-based information incident to a branch point differs from that which is emitted from that branch point.

In the study described here, the propagation of random trains of impulses across single or serially arranged symmetrical branch points in unmyelinated axons was simulated. Single-impulse propagation illustrated the axial modifications of the point-to-point conduction velocity (hereafter: "CV(x)") through primary and secondary serial branch points. Poisson-like random stimulation elicited wide-band impulse trains to assess possible frequency-modulated distortion during impulse propagation within the arborization. Possible modifications due to periaxonal K+ accumulation or the kinetic description of Na+ conductance were also considered.

DOI
10.1201/9780203390979.ch18
Citation Information
Melvyn D. Goldfinger. "Highly Efficient Propagation of Random Impulse Trains Across Unmyelinated Axonal Branch Points: Modifications by Periaxonal K+ Accumulation and Sodium Channel Kinetics" Modeling in the Neurosciences: From Biological Systems to Neuromimetic Robotics (2005) p. 480 - 529 ISSN: 0415328683
Available at: http://works.bepress.com/melvyn_goldfinger/11/