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Management of Sepsis: Early Resuscitation
Clinics in Chest Medicine
  • Emanuel Rivers
  • Victor Coba
  • Alvaro Visbal
  • Melissa L. Whitmill, Wright State University
  • David Amponsah
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Key links in the chain of survival for the management of severe sepsis and septic shock are early identification and comprehensive resuscitation of high-risk patients. Multiple studies have shown that the first 6 hours of early sepsis management are especially important from a diagnostic, pathogenic, and therapeutic perspective, and that steps taken during this period can have a significant impact on outcome. The recognition of this critical time period and the robust outcome benefit realized in previous studies provides the rationale for adopting early resuscitation as a distinct intervention. Sepsis joins trauma, stroke, and acute myocardial infarction in having “golden hours,” representing a critical opportunity early on in the course of disease for actions that offer the most benefit.
Citation Information
Emanuel Rivers, Victor Coba, Alvaro Visbal, Melissa L. Whitmill, et al.. "Management of Sepsis: Early Resuscitation" Clinics in Chest Medicine Vol. 29 Iss. 4 (2008) p. 689 - 704 ISSN: 0272-5231
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