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Article
Management of Sepsis: Early Resuscitation
Clinics in Chest Medicine
  • Emanuel Rivers
  • Victor Coba
  • Alvaro Visbal
  • Melissa L. Whitmill, Wright State University
  • David Amponsah
Document Type
Article
Publication Date
12-1-2008
Abstract
Key links in the chain of survival for the management of severe sepsis and septic shock are early identification and comprehensive resuscitation of high-risk patients. Multiple studies have shown that the first 6 hours of early sepsis management are especially important from a diagnostic, pathogenic, and therapeutic perspective, and that steps taken during this period can have a significant impact on outcome. The recognition of this critical time period and the robust outcome benefit realized in previous studies provides the rationale for adopting early resuscitation as a distinct intervention. Sepsis joins trauma, stroke, and acute myocardial infarction in having “golden hours,” representing a critical opportunity early on in the course of disease for actions that offer the most benefit.
DOI
10.1016/j.ccm.2008.06.005
Citation Information
Emanuel Rivers, Victor Coba, Alvaro Visbal, Melissa L. Whitmill, et al.. "Management of Sepsis: Early Resuscitation" Clinics in Chest Medicine Vol. 29 Iss. 4 (2008) p. 689 - 704 ISSN: 0272-5231
Available at: http://works.bepress.com/melissa_whitmill/14/