About Melissa A. Kennedy
My research is focused on viruses. I have a focus on viruses of cats (feline coronavirus, calicivirus, lentivirus). I have an interest in infectious diseases of wildlife, particularly viruses of endangered animals. I am also interested in improving and developing diagnostics for viral diseases, as well as new antiviral therapies.
Zoology, Ecology and Evolutionary Biology, Terrestrial and Aquatic Ecology, Immunology and Infectious Disease, Veterinary Medicine, Veterinary Infectious Diseases, Veterinary Microbiology and Immunobiology, Veterinary Preventive Medicine, Epidemiology, and Public Health, and Veterinary Toxicology and Pharmacology
Diagnostic Sciences & Education
A205 Veterinary Teaching Hospital
2407 River Drive
Knoxville, TN 37996-4543
Sensitivity and specificity of a nested polymerase chain reaction for ...
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians (2010)
Feline immunodeficiency virus (FIV) is a lentivirus in the Retroviridae family that causes lifelong infection in domestic cats. The lentivirus ...
Detection of feline panleukopenia virus using a commercial ELISA for ...
Veterinary therapeutics : research in applied veterinary medicine (2009)
Feline panleukopenia virus (FPV) is a significant pathogen of cats. Rapid virus detection is critical for treatment and management, especially ...
Genetic analysis of feline caliciviruses associated with a hemorrhagic-like disease
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc (2005)
Feline calicivirus (FCV) is 1 of the most common causes of upper respiratory tract disease in cats. Other disease syndromes ...
Detection of feline coronavirus in captive Felidae in the USA
Feline coronavirus (FCoV) is an important pathogen of domestic and nondomestic Felidae. Investigation into the prevalence of FCoV in exotic Felidae has relied primarily on serology. The usefulness of genetic detection of FCoV using reverse transcription and nested polymerase chain reaction (RT/nPCR) for viral screening was investigated. Seventy-five biologic samples, primarily feces, from captive felids from 11 institutions were tested using PCR. Serum samples collected from all but 12 of these animals were tested for antibodies to type I and type II FCoV by indirect immunofluorescence. Twenty-four animals were positive using RT/nPCR for virus. Twenty-nine animals were seropositive to type I and/or type II FCoV. From serologic data, infection with a virus antigenically related to FCoV type I occurred most commonly. Serology did not correlate with virus shedding because 13 animals were seronegative to FCoV type I and II but positive using RT/nPCR for virus. Conversely, 20 animals were seropositive but negative using RT/nPCR for FCoV. Some of the populations in which virus was detected had experienced health problems, including feline infectious peritonitis (FIP), necrotizing colitis, and mild enteritis. In addition to its role in FIP, this virus may play a role in gastrointestinal diseases of infected animals. This study demonstrates that FCoV is a significant infectious agent of captive felids because over half of the animals tested were positive by viral genetic detection, serology, or both. Dependence upon one method for detection of infection is unreliable. (2002)
Feline coronavirus (FCoV) is an important pathogen of domestic and nondomestic Felidae. Investigation into the prevalence of FCoV in exotic ...
Detection of feline coronavirus infection in captive cheetahs (Acinonyx jubatus ...
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians (2001)
Feline coronavirus genetic elements were detected by polymerase chain reaction from blood, fecal samples, and effusive fluid collected from 33 ...
Virucidal efficacy of the newer quaternary ammonium compounds
Journal of the American Animal Hospital Association (1995)
The virucidal activity of several disinfectants containing newer generation quaternary ammonium compounds (QACs) as their active ingredients was evaluated. Disinfectants ...