My group focuses on synthesizing macromolecular materials, which stimulate and influence cell functions including proliferation, differentiation and internalization. These materials incorporate bio-functional species in a controlled manner with the goal of directing cell responses. We are developing new peptide-and DNA-based ligands and nanoparticle reporters for the characterization of molecular signatures, which occur during these processes. The knowledge gained from these studies impacts numerous areas in biomaterials, regenerative medicine, and the detection of disease states, including cancer.