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About Matthew Sherwood

My research interests include investigating brain function and neurological disorders using novel neuroimaging techniques including functional MRI, pseudo-continuous arterial spin labeling, diffusion tensor imaging and magnetic resonance spectroscopy. In my past work, I have investigated working memory through real-time functional magnetic resonance imaging neurofeedback training (fMRI-NFT). In this work, we found that self-neuromodulation of the left Dorsolateral Prefrontal Cortex increased significantly across the five training days. Further, we found that working memory, examined before and after training, improved significantly more in the group receiving real-time neurofeedback than a behavior-only control group. This body of work provides the foundation for new and innovative techniques to study and augment cognition in healthy individuals. In another study, I investigated neural correlates of learning a visual object recognition task in healthy individuals. This work, a Phase II Office of Naval Research Small Business Innovation Research project, included collaborations with industry partners (engineers, computer scientists, data miners) and university faculty. Using MRI, we successfully identified anatomical regions responding to a realistic task. From this data, a cognitive model was developed and implemented to aid rapid training of said task. In a third project, I investigated the neural correlates of mirror imaging bias. We found that activity in the Inferior Frontal Gyrus (IFG) is associated with mirror imaging. Furthermore, N-acetyl aspartate (NAA) to Creatine (Cr) and NAA to Choline (Cho) ratios measured from MR Spectroscopy can reliably predict individual susceptibility to mirror imaging. Other projects involve developing innovative treatments for tinnitus based upon fMRI-NFT, using neuroimaging techniques to uncover cognitive effects of transcranial direct current stimulation, and to study the hemodynamic response of the brain to hypoxic conditions.

Positions

March 2022 - Present Founding Director, Wright State University Center of Neuroimaging and Neuro-Evaluation of Cognitive Technologies
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March 2022 - Present Research Associate Professor, Wright State University Neuroscience, Cell Biology & Physiology
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September 2020 - April 2022 Senior Neuroscientist, Science & Space, KBR Inc.
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January 2018 - November 2020 Neuroscience Consultant, Inforscitex Corporation
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August 2017 - December 2020 Adjunct Faculty, Wright State University Biomedical, Industrial, & Human Factors Engineering
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July 2016 - September 2020 Research Engineer II, Wright State University Biomedical, Industrial, & Human Factors Engineering
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May 2012 - June 2016 Medical Research Engineer, Wright State University Wright State Research Institute
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Curriculum Vitae




Grants

2021 - 2024 Airmen Rediness & Medical Readiness, Contract FA8640-21-C-6277
U.S. Air Force
Air Force Resarch Laboratory
Role: Investigator
$4,649,078
2022 - 2023 Cognitive and Neurology Research I
U.S. Air Force
Air Force Resarch Laboratory
Role: Site Principal Investigator
$101,099
2022 - 2023 Cognitive and Neurology Research II
U.S. Air Force
Air Force Resarch Laboratory
Role: Site Principal Investigator
$442,493
2022 - 2023 fMRI Scanning to Examine the Neural Effects of Transcutaneous Vagus Nerve Stimulation on Learning
U.S. Air Force
Air Force Resarch Laboratory
Role: Site Principal Investigator
$305,690
2020 - 2021 To Establish a Joint DOD and WSU Center of Neuroimaging and Neuro-Evaluation of Cognitive Technologies, Contract FA9550-20-1-0239,
U.S. Air Force
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Role: Principal Investigator
$1,100,000
2020 - 2021 To Establish a Joint DOD and WSU Center of Neuroimaging and Neuro-Evaluation of Cognitive Technologies, Proposal #1676,
State of Ohio
Ohio Department of Higher Education
Role: Principal Investigator
$200,000
2018 - 2020 Cerebral Hemodynamics of Hypoxia and Fatigue, Contract N62645-18-C-4017
U.S. Navy
Naval Medical Research Unit
Role: Principal Investigator
$500,797
2016 - 2020 Alternate Tinnitus Management Techniques Developed Using Blood-Oxygen-Level-Dependent MRI with Neurofeedback
U.S. Air Force
59th Medical Wing
Role: Principal Investigator
$1,759,612
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Education

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December 2022 Master of Business Administration, Wright State University
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July 2017 Ph.D. Engineering, Wright State University ‐ Medical and Biolgocial Systems
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December 2013 Master of Science, Engineering, Wright State University ‐ Biomedical Image and Signal Processing
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June 2011 Bachelor of Science, Biomedical Engineering, Wright State University
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Recent Works (16)