In a 2000 article in Industrial Marketing Management, “Issues in Supply Chain Management,” Lambert and Cooper presented a framework for Supply Chain Management (SCM) as well as issues related to how it should be implemented and directions for future research. The framework was comprised of eight cross-functional, cross-firm business processes that could be used as a new way to manage relationships with suppliers and customers. It was based on research conducted by a team of academic researchers working with a group of executives from non-competing firms that had been meeting regularly since 1992 with the objective of improving SCM theory and practice. The research has continued for the past 16 years and now covers a total of 25 years. In this paper, we review the progress that has been made in the development and implementation of the proposed SCM framework since 2000 and identify opportunities for further research.