Skip to main content
Article
Genotype-Phenotype Diversity of Beta-Thalassemia in Malaysia: Treatment Options and Emerging Therapies
Medical Journal of Malaysia (2010)
  • maryanne jin ai tan, maryanne, University of Malaya
Abstract

The haemoglobinopathies and thalassemias represent the most common inherited monogenic disorders in the world1. Beta-thalassaemia major is an ongoing public health problem in Malaysia2. Prior to 2004, the country had no national policy for screening and registry for thalassemia. In the absence of a national audit, the true figure of the extent of thalassemia in the Malaysian population was largely presumptive from micro-mapping studies from various research workers in the country. The estimated carrier rate for beta-thalassemia in Malaysia is 3.5-4%. There were 4768 transfusion dependent thalassemia major patients as of May 2010 (Data from National Thalassemia Registry).

Keywords
  • Genotype-phenotype,
  • thalassemia,
  • Malaysia,
  • treatment options
Publication Date
December, 2010
Citation Information
maryanne jin ai tan. "Genotype-Phenotype Diversity of Beta-Thalassemia in Malaysia: Treatment Options and Emerging Therapies" Medical Journal of Malaysia Vol. 65 (2010)
Available at: http://works.bepress.com/maryanne_tan/9/