Failed treatment of amelanotic lentigo maligna with imiquimod followed by pigment productionDermatology Publications and Presentations
UMMS AffiliationDepartment of Medicine, Division of Dermatology
Document TypeLetter to the Editor
SubjectsAdministration, Topical; Aminoquinolines; Biopsy, Needle; Female; Follow-Up Studies; Humans; Hutchinson's Melanotic Freckle; Immunohistochemistry; Melanoma, Amelanotic; Middle Aged; Neoplasm Recurrence, Local; Nose; Risk Assessment; Skin Neoplasms; Treatment Outcome
AbstractA melanotic lentigo maligna (ALM) represents a small subset of lentigo maligna (LM) that lacks pigment. At least 2 cases of ALM responsive to imiquimod therapy with short-term follow-up have been reported. We report herein a case of ALM that failed to respond to imiquimod treatment. Furthermore, after therapy was initiated, the ALM began to produce pigment and transformed to LM.
DOI of Published Version10.1001/archdermatol.2010.237
Martires KJ, Capaldi L, Pattee SF, Maloney ME, Bordeaux JS. Failed treatment of amelanotic lentigo maligna with imiquimod followed by pigment production. Arch Dermatol. 2010 Sep;146(9):1047-8. doi: 10.1001/archdermatol.2010.237.
Related ResourcesLink to Article in PubMed
Citation InformationKathryn J. Martires, Laura Capaldi, Sean F. Pattee, Mary E. Maloney, et al.. "Failed treatment of amelanotic lentigo maligna with imiquimod followed by pigment production" Vol. 146 Iss. 9 (2010) ISSN: 0003-987X (Linking)
Available at: http://works.bepress.com/mary_maloney/26/