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Evidence-based Toxicology for the 21st Century: Opportunities and Challenges
Toxicology and Animal Models in Research Collection
  • Martin L. Stephens, Johns Hopkins University
  • Melvin E. Andersen, The Hamner Institutes for Health Sciences
  • Richard A. Becker, American Chemistry Council
  • Kellyn Betts, Freelance Writer and Editor
  • Kim Boekelheide, Brown University
  • Ed Carney, Dow Chemical
  • Robert Chapin, Pfizer Global R&D
  • Dennis Devlin, Exxon Mobil
  • Suzanne C. Fitzpatrick, U.S. Food and Drug Administration
  • John R. Fowle, III, U.S. Environmental Protection Agency
  • Patricia Harlow, U.S. Food and Drug Administration
  • Thomas Hartung, Johns Hopkins University
  • Sebastian Hoffman, seh consulting + services
  • Michael P. Holsapple, Battelle
  • Abigail Jacobs, U.S. Food and Drug Administration
  • Richard Judson, U.S. Environmental Protection Agency
  • Olga Naidenko, Environmental Working Group
  • Tim Pastoor, Syngenta
  • Grace Patlewicz, DuPont Haskell Global Centers for Health and Environmental Sciences
  • Andrew Rowan, Humane Society International
  • Roberta Scherer, Johns Hopkins University
  • Rashid Shaikh, Health Effects Institute
  • Ted Simon, Ted Simon, LLC
  • Douglas Wolf, U.S. Environmental Protection Agency
  • Joanne Zurlo, Johns Hopkins University
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The Evidence-based Toxicology Collaboration (EBTC) was established recently to translate evidence-based approaches from medicine and health care to toxicology in an organized and sustained effort. The EBTC held a workshop on “Evidence-based Toxicology for the 21st Century: Opportunities and Challenges” in Research Triangle Park, North Carolina, USA on January 24-25, 2012. The presentations largely reflected two EBTC priorities: to apply evidence-based methods to assessing the performance of emerging pathwaybased testing methods consistent with the 2007 National Research Council report on “Toxicity Testing in the 21st Century” as well as to adopt a governance structure and work processes to move that effort forward. The workshop served to clarify evidence-based approaches and to provide food for thought on substantive and administrative activities for the EBTC. Priority activities include conducting pilot studies to demonstrate the value of evidence-based approaches to toxicology, as well as conducting educational outreach on these approaches.


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Citation Information
Stephens, M., Andersen, M., Becker, R., Betts, K., Boekelheide, K., Carney, E., Chapin, R., Devlin, D., Fitzpatrick, S., Fowle III, J., Harlow, P., Hartung, T., Hoffmann, S., Holsapple, M., Jacobs, A., Judson, R., Naidenko, O., Pastoor, T., Patlewicz, G., Rowan, A., Scherer, R., Shaikh, R., Simon, T., Wolf, D. and Zurlo, J. (2013) “Evidence-based toxicology for the 21st century: Opportunities and challenges”, ALTEX - Alternatives to animal experimentation, 30(1), pp. 74-103. doi: 10.14573/altex.2013.1.074.