This paper introduces generalized zeros and hence disconjugacy of nth order linear dynamic equations, which cover simultaneously as special cases (among others) both differential equations and difference equations. We also define Markov, Fekete, and Descartes interpolating systems of functions. The main result of this paper states that disconjugacy is equivalent to the existence of any of the above interpolating systems of solutions and that it is also equivalent to a certain factorization representation of the operator. The results in this paper unify the corresponding theories of disconjugacy for nth order linear ordinary differential equations and for nth order linear difference equations.