Article
Effects of Genetic Immunity and Resistance on Endemics
Applied Mathematics and Computation
Document Type
Article
Publication Date
4-1-2008
DOI
10.1016/j.amc.2007.08.009
Disciplines
- Education and
- Mathematics
Abstract
We incorporate basic genetics into an SIS endemic model of a disease that is spread primarily by individual–individual contact after it is introduced into the population. We illustrate that if a homozygote is immune to the disease or is resistant to the effects of the disease, the corresponding allele goes to fixation. On the other hand, if the heterozygote is immune to the disease or is resistant to the effects of the disease, polymorphism usually occurs. However, under some conditions, polymorphism may not occur.
Citation Information
James P. Braselton, Martha L. Abell and Lorraine Braselton. "Effects of Genetic Immunity and Resistance on Endemics" Applied Mathematics and Computation Vol. 197 Iss. 2 (2008) p. 733 - 744 ISSN: 0096-3003 Available at: http://works.bepress.com/martha_abell/6/