Instant insight: think outside the cellFaculty of Science - Papers (Archive)
AbstractProteins perform many different functions critical for life, from building our muscle structure to digesting our food. These large biological molecules each have a unique three-dimensional shape which they require to perform their function. In protein deposition diseases (PDDs), however, a disease-specific protein molecule unfolds from its normal shape and assembles together with like molecules into insoluble rod-shaped fibrils. These protein deposits can be found in the brain, skeletal tissue and various organs; in some cases they may become large enough to disrupt tissue structure and function.
Link to publisher version (URL)Highlights in Chemical Biology
Citation InformationMark R Wilson and Justin J Yerbury. "Instant insight: think outside the cell" (2008)
Available at: http://works.bepress.com/mark_wilson/51/