This article is a research note addressing various theoretical and methodological issues in the measurement and analysis of religiosity and secularism and their relationship to quantifiable measures of social health in advanced and prosperous democracies. Particular attention is given to cross-national frameworks for studying religiosity and secularism as well as to the conceptualization and statistical analysis of these notions for research design. Various procedural suggestions regarding the use of comparative frameworks are presented to assist in the development and implementation of future studies gauging the impact of worldview commitments upon societal wellbeing.