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Immunity induced in rats vaccinated with toxoid prepared from heat-labile toxin produced by Pasteurella multocida serogroup D
Veterinary Microbiology (1991)
  • J. R. Thurston, United States Department of Agriculture
  • R. B. Rimler, United States Department of Agriculture
  • Mark R. Ackermann, United States Department of Agriculture
  • N. F. Cheville, United States Department of Agriculture
  • J. M. Sacks, United States Department of Agriculture
Abstract

Rats were vaccinated with a toxoid (D-toxoid) prepared from purified heat-labile toxin (D-toxin) produced by Pasteurella multocida serogroup D. Vaccination of rats with D-toxoid prevented death and other effects of D-toxin (hepatic necrosis, development of elevated leukocyte counts, lymphopenia, neutrophilia, and elevated complement titers) that occurred in phosphate buffered saline (PBS)-vaccinated control rats.

Publication Date
April, 1991
Publisher Statement
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.
Citation Information
J. R. Thurston, R. B. Rimler, Mark R. Ackermann, N. F. Cheville, et al.. "Immunity induced in rats vaccinated with toxoid prepared from heat-labile toxin produced by Pasteurella multocida serogroup D" Veterinary Microbiology Vol. 27 Iss. 2 (1991)
Available at: http://works.bepress.com/mark_ackermann/57/