Article
Coordinated Expression of Tracheal Antimicrobial Peptide and Inflammatory-Response Elements in the Lungs of Neonatal Calves with Acute Bacterial Pneumonia
Infection and Immunity
Document Type
Article
Disciplines
Publication Date
5-1-2003
DOI
10.1128/IAI.71.5.2950-2955.2003
Abstract
Lung tissue removed from neonatal calves with acute Mannheimia haemolyticapneumonia showed that rapid up-regulation of the basal mRNA expression of tracheal antimicrobial peptide (TAP), NF-κB, and intercellular adhesion molecule 1 occurred after infection; TAP and interleukin 8 expression were highly correlated. This work suggests that the coordinated expression of β-defensin and inflammatory elements occurs during bacterial pneumonia.
Copyright Owner
American Society for Microbiology
Copyright Date
2003
Language
en
File Format
application/pdf
Citation Information
Jessica M. Caverly, Gill Diamond, Jack M. Gallup, Kim A. Brogden, et al.. "Coordinated Expression of Tracheal Antimicrobial Peptide and Inflammatory-Response Elements in the Lungs of Neonatal Calves with Acute Bacterial Pneumonia" Infection and Immunity Vol. 71 Iss. 5 (2003) p. 2950 - 2955 Available at: http://works.bepress.com/mark_ackermann/1/
This article is from Infection and Immunity 71, no. 5 (May 2003): 2950–2955, doi:10.1128/IAI.71.5.2950-2955.2003.