Coordinated Expression of Tracheal Antimicrobial Peptide and Inflammatory-Response Elements in the Lungs of Neonatal Calves with Acute Bacterial PneumoniaInfection and Immunity
AbstractLung tissue removed from neonatal calves with acute Mannheimia haemolyticapneumonia showed that rapid up-regulation of the basal mRNA expression of tracheal antimicrobial peptide (TAP), NF-κB, and intercellular adhesion molecule 1 occurred after infection; TAP and interleukin 8 expression were highly correlated. This work suggests that the coordinated expression of β-defensin and inflammatory elements occurs during bacterial pneumonia.
Copyright OwnerAmerican Society for Microbiology
Citation InformationJessica M. Caverly, Gill Diamond, Jack M. Gallup, Kim A. Brogden, et al.. "Coordinated Expression of Tracheal Antimicrobial Peptide and Inflammatory-Response Elements in the Lungs of Neonatal Calves with Acute Bacterial Pneumonia" Infection and Immunity Vol. 71 Iss. 5 (2003) p. 2950 - 2955
Available at: http://works.bepress.com/mark_ackermann/1/