From an informal survey of more than 20 peer-reviewed journals, we selected topics where evidence from recent research is changing our approach to common problems we see in family medicine—osteoporosis and asthma—and where new information has identified an emerging problem, hepatitis C. Data on the treatment of depression with St John's wort and the value of continuity of care are also discussed. Research articles were identified from MEDLINE searches and selected based on their validity and relevance to clinical practice.