Article
Data on IL-10R neutralization-induced chronic colitis in Lipocalin 2 deficient mice on BALB/c background
Data in Brief
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
4-1-2017
DOI
10.1016/j.dib.2017.03.002
Abstract
The data herein is related to the research article entitled “Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis” (Singh et al., 2016) [1] where we have demonstrated that C57BL/6 Lipocalin 2 deficient mice (Lcn2KO) developed chronic colitis upon anti-interleukin-10 receptor (αIL-10R) monoclonal antibody administration. In the present article, we evaluated the susceptibility of BALB/c Lcn2KO mice and their WT littermates to the αIL-10R neutralization-induced chronic colitis. Our data showed that αIL-10R mAb-treated BALB/c Lcn2KO mice exhibited severe chronic colitis (i.e., splenomegaly, colomegaly, colonic pathology, and incidence of rectal prolapse) when compared to WT mice.
Creative Commons License
Creative Commons Attribution 4.0 International
Copyright Owner
The Authors
Copyright Date
2017
Language
en
File Format
application/pdf
Citation Information
Vishal Singh, Beng San Yeoh, Marit Nilsen-Hamilton, Thorsten Berger, et al.. "Data on IL-10R neutralization-induced chronic colitis in Lipocalin 2 deficient mice on BALB/c background" Data in Brief Vol. 11 (2017) p. 588 - 592 Available at: http://works.bepress.com/marit-nilsen-hamilton/37/
This article is published as Singh, Vishal, Beng San Yeoh, Marit Nilsen-Hamilton, Thorsten Berger, Tak W. Mak, and Matam Vijay-Kumar. "Data on IL-10R neutralization-induced chronic colitis in Lipocalin 2 deficient mice on BALB/c background." Data in brief 11 (2017): 588-592. doi: 10.1016/j.dib.2017.03.002.