Fluorinated Analogs of Malachite Green: Synthesis and ToxicityMolecules
Publication VersionPublished Version
AbstractA series of fluorinated analogs of malachite green (MG) have been synthesizedand their toxicity to Saccharomyces cerevisiae and a human ovarian epithelial cell lineexamined. The toxicity profiles were found to be different for these two species. Twoanalogs, one with 2,4-difluoro substitution and the other with 2-fluoro substitution seem tobe the most promising analogs because they showed the lowest toxicity to the human cells.
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Citation InformationGeorge A. Kraus, Insik Jeon, Marit Nilsen-Hamilton, Ahmed M. Awad, et al.. "Fluorinated Analogs of Malachite Green: Synthesis and Toxicity" Molecules Vol. 13 Iss. 4 (2008) p. 986 - 994
Available at: http://works.bepress.com/marit-nilsen-hamilton/18/