Skip to main content
Article
Fluorinated Analogs of Malachite Green: Synthesis and Toxicity
Molecules
  • George A. Kraus, Iowa State University
  • Insik Jeon, Iowa State University
  • Marit Nilsen-Hamilton, Iowa State University
  • Ahmed M. Awad, Iowa State University
  • Jayeeta Banerjee, Iowa State University
  • Bahram Parvin, Lawrence Berkeley Laboratory
Document Type
Article
Publication Version
Published Version
Publication Date
1-1-2008
DOI
10.3390/molecules13040986
Abstract
A series of fluorinated analogs of malachite green (MG) have been synthesizedand their toxicity to Saccharomyces cerevisiae and a human ovarian epithelial cell lineexamined. The toxicity profiles were found to be different for these two species. Twoanalogs, one with 2,4-difluoro substitution and the other with 2-fluoro substitution seem tobe the most promising analogs because they showed the lowest toxicity to the human cells.
Comments

This is an article from Molecules 13 (2008): 986, doi:10.3390/molecules13040986. Posted with permission.

Rights
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright Owner
MDPI
Language
en
File Format
application/pdf
Citation Information
George A. Kraus, Insik Jeon, Marit Nilsen-Hamilton, Ahmed M. Awad, et al.. "Fluorinated Analogs of Malachite Green: Synthesis and Toxicity" Molecules Vol. 13 Iss. 4 (2008) p. 986 - 994
Available at: http://works.bepress.com/marit-nilsen-hamilton/18/