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Article
Differential surface stress sensor for detection of chemical and biological species
Applied Physics Letters
  • K. Kang, Iowa State University
  • Marit Nilsen-Hamilton, Iowa State University
  • Pranav Shrotriya, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
1-1-2008
DOI
10.1063/1.2996411
Abstract
We report a sensor consisting of two micromachined cantilevers (a sensing/reference pair) that is suitable for detection of chemical and biological species. The sensing strategy involves coating the sensing cantilever with receptors that have high affinities for the analyte. The presence of analyte is detected by determining the differential surface stress associated with its adsorption/absorption to the sensing cantilever. An interferometric technique is utilized to measure the differential bending of the sensing cantilever with respect to reference. Surface stress associated with hybridization of single stranded DNA is measured to demonstrate the unique advantages of the sensor.
Comments

This is an article from Applied Physics Letters 93 (2008): 143107, doi:10.1063/1.2996411. Posted with permission.

Copyright Owner
American Institute of Physics
Language
en
File Format
application/pdf
Citation Information
K. Kang, Marit Nilsen-Hamilton and Pranav Shrotriya. "Differential surface stress sensor for detection of chemical and biological species" Applied Physics Letters Vol. 93 (2008) p. 143107
Available at: http://works.bepress.com/marit-nilsen-hamilton/14/