Differential surface stress sensor for detection of chemical and biological speciesApplied Physics Letters
Publication VersionPublished Version
AbstractWe report a sensor consisting of two micromachined cantilevers (a sensing/reference pair) that is suitable for detection of chemical and biological species. The sensing strategy involves coating the sensing cantilever with receptors that have high affinities for the analyte. The presence of analyte is detected by determining the differential surface stress associated with its adsorption/absorption to the sensing cantilever. An interferometric technique is utilized to measure the differential bending of the sensing cantilever with respect to reference. Surface stress associated with hybridization of single stranded DNA is measured to demonstrate the unique advantages of the sensor.
Copyright OwnerAmerican Institute of Physics
Citation InformationK. Kang, Marit Nilsen-Hamilton and Pranav Shrotriya. "Differential surface stress sensor for detection of chemical and biological species" Applied Physics Letters Vol. 93 (2008) p. 143107
Available at: http://works.bepress.com/marit-nilsen-hamilton/14/