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Article
Functional nucleic acid probes and uses thereof
Iowa State University Patents
  • Marit Nilsen-Hamilton, Iowa State University
Document Type
Patent
Publication Date
10-3-2006
Abstract

The present invention provides functional nucleic acid probes, and methods of using functional nucleic acid probes, for binding a target to carry out a desired function. The probes have at least one functional nucleic acid, at least one regulating nucleic acid, and at least one attenuator. The functional nucleic acid is maintained in an inactive state by the attenuator and activated by the regulating nucleic acid only in the presence of a regulating nucleic acid target. In its activated state the functional nucleic acid can bind to its target to carry out a desired function, such as generating a signal, cleaving a nucleic acid, or catalyzing a reaction.

Patent Number
US 7,115,369 B2
ISURF Reference Number

2711

Assignee
Iowa State University Research Foundation, Inc.,
Application Number
US 10/096,872
Date Filed
3-14-2002
Language
en
Date Available
2013-09-30
File Format
application/pdf
Citation Information
Marit Nilsen-Hamilton. "Functional nucleic acid probes and uses thereof" (2006)
Available at: http://works.bepress.com/marit-nilsen-hamilton/11/