Skip to main content
Article
Changes in cell density and morphology of selected cells of the ageing human dental pulp.pdf
Gerondontology (2014)
  • Sulinda Daud, Segi University College
  • Phrabhakaran Nambiar, Faculty of Dentistry, University of Malaya
  • Mohammad Zakir Hossain, University of Malaya
  • Mas Rizal Ab Rahman, Faculty of Dentistry, University of Malaya
  • Marina Mohd Bakri, University of Malaya
Abstract
Objectives                                                                
The aim of this study was to determine the changes in cell density and morphology of selected cells of the aging human dental pulp.
Background
Changes in cell density and morphology of dental pulp cells over time may affect their capability to respond to tooth injury.
Materials and methods
One hundred thirty-one extracted teeth were obtained from individuals between the ages of 6 and 80 years. The apical 1/3 of the root region was removed from all teeth prior to routine processing for producing histological slides. The histology slides were used to study the changes in cell density and morphology of selected pulp cells; odontoblasts, subodontoblasts and fibroblasts in the crown and root regions of the dental pulp.Student’s t-test and one-way ANOVA were used for statistical analyses.
Results
In all age groups, the cell density for all type of cells was found to be higher in the crown than in the root (P< 0.05).In general, the pulp cell density was found to decrease with age in both the crown and root regions. However, it was noted that the reduction of coronal odontoblasts occurred later in life (40-49 years) when compared to that of subodontoblasts or fibroblasts (30-39 years).
Keywords
  • ageing,
  • histology,
  • odontoblast,
  • pulp
Publication Date
2014
DOI
10.1111/ger.12154
Citation Information
Sulinda Daud, Phrabhakaran Nambiar, Mohammad Zakir Hossain, Mas Rizal Ab Rahman, et al.. "Changes in cell density and morphology of selected cells of the ageing human dental pulp.pdf" Gerondontology Vol. 33 Iss. 3 (2014) p. 315 - 321 ISSN: 0734-0664
Available at: http://works.bepress.com/marinamohdbakri/5/