SelectedWorks - Margaret Stratton

Contact

Selected Works of Margaret Stratton

Assistant Professor

Works
About

×

About Margaret Stratton

Present	Assistant Professor, University of Massachusetts Amherst
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Cancel

Biochemistry, Biophysics, and Structural Biology and Molecular Biology

Molecular Mechanism of activation-triggered subunit exchange in human CaMKII

M Bhattacharyya, Margaret M Stratton, Catherine Going, Yongjian Huang, et al.

Activation triggers the exchange of subunits in Ca2+/calmodulin-dependent protein kinase II (CaMKII), an oligomeric enzyme that is critical for learning, ...

Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of ...

Margaret M Stratton, I H Lee, M Bhattacharyya, S M Christensen, et al.

The activation of the dodecameric Ca2+/calmodulin dependent kinase II (CaMKII) holoenzyme is critical for memory formation. We now report that ...

Converting a protein into a switch for biosensing and functional ...

Protein Science (2011)

Margaret M Stratton and S N Loh

Proteins that switch conformations in response to a signaling event (e.g., ligand binding or chemical modification) present a unique solution ...

On the mechanism of protein fold-switching by a molecular sensor

Proteins (2010)

Margaret M Stratton and S N Loh

Alternate frame folding (AFF) is a mechanism by which conformational change can be engineered into a protein. The protein structure ...

Probing local structural fluctuations in myoglobin by size-dependent thiol-disulfide exchange

Protein Science (2010)

Margaret M Stratton, S N Loh, T A Cutler and J H Ha

All proteins undergo local structural fluctuations (LSFs) or breathing motions. These motions are likely to be important for function but ...