Supersymmetry and extra dimensions are the two most promising candidates for new physics at the TeV scale. Supersymmetric particles or extra-dimensional effects could soon be observed at the Large Hadron Collider. We propose a simple but effective method to discriminate the two models: the analysis of isolated leptons with high transverse momentum. Black hole events are simulated with the CATFISH black hole generator. Supersymmetry simulations use a combination of PYTHIA and ISAJET, the latter providing the mass spectrum. Our results show that the measure of the dilepton invariant mass provides a promising signature to differentiate supersymmetry and black hole events at the Large Hadron Collider. Analysis of event-shape variables and multilepton events complement and strengthen this conclusion.