Healthy heart valves are essential for proper blood circulation. Their role is to ensure unidirectional blood flow in the circulatory system. They consist of different tissue layers and are capable of adapting and remodeling their tissue composition according to the hemodynamic environments surrounding them [1-3]. The mitral and tricuspid valves are located between the atria and ventricles while the pulmonary valve is found intersecting the right ventricle and the pulmonary artery. The aortic valve resides between the left ventricle and the aorta.